Review Article

The Effectiveness of Music in Pediatric Healthcare: A Systematic Review of Randomized Controlled Trials

Table 1

Characteristics of eligible studies.

StudyParticipantsInterventionDosageQuality
First Author, YearCountryRecruitment settingStudy designN (n males)Clinical populationAge range (years)TreatmentMusic delivery Music type Participant involvement Delivery format Intervention format No. of sessions (time)No. of weeksPEDro score (sum/10)

Learning and developmental disorders

Aldridge, 1995 [33]GermanyPrivate practice clinicCrossover RCT8 (2)Developmental delay4–6.5Group 1 : Music therapy (Nordoff & Robbins adaptation); Group 2 : Initial non-treatment group; cross-over occurred 3 timesMTLAOI24 (30 m)485

Claussen, 1997 [34]USASpecial education facilityParallel RCT21 (12)Learning disabilities9–11Group 1: Familiar music; Group 2: Verbal condition; both groups rehearsed multiplication problemsRRPOS1 ( 60 m) 13

Buday, 1995 [35]USAPublic school (special education program)Crossover RCT10 (8)Autism4–9Group 1 : Music condition; Group 2 : Rhythm condition; 5 trials/dayRRPOS8 (n/a)26

Kim, 2008 [36]KoreaAmbulatory care clinicCrossover RCT10 (10)Autistic disorder3–5Group 1 : Block of improvisational music therapy (instrumental) + block of play (toys); Group 2: Reversed block orderMTLAOI12 (30 m)244
Pratt, 1995 [37]CanadaCommunityParallel RCT19 (17)ADD or ADHD6–18Neurofeedback sessions with or without background classical musicRRPOS39 ( 60 m)133

Rickson, 2003 [38]New ZealandSpecial education residential facilityParallel RCT15 (15)Intellectual, social and emotional deficits including ADD/ADHD11–15Group 1 : Waitlist control group; Group 2 & Group 3 : Music therapy sessions (favorite music; instrumental and rhythym based activities).MTL & RA & PGS & I16 (30–45 m)83

Rickson, 2006 [39]New ZealandSpecial education residential facilityCrossover RCT13 (13)ADHD and other comorbid disorders11–16Group 1 : Waitlist control group. Group 2 : 1 block of improvisational + 1 block of instructional music therapy. Group 3 : reversed orderMTLAGS & I16 (30–45 m)202

Stressful life events

Baker, 2006 [40]AustraliaESL secondary schoolCrossover RCT31 (11)Newly arrived immigrant and refugee adolescents11–16Groups 1 : 2 blocks music therapy (instrumental and song based activities) + 2 blocks no music therapy; Group 2 : reversed orderMTL & RA & PGS & I20 (30–40 m)206
DeLucia-Waack, 2007 [41]USAElementary schoolCluster parallel RCT134 (67)Children from divorced and/or separated families5–10Group 1 : Music intervention (song based); Group 2 : Traditional psychoeducationHPRAGS8 (45 m)83

Hilliard, 2007 [42]USAElementary schoolsCluster Parallel RCT26 (14)Children experiencing bereavement5–11Group 1 (n=8): Orff-based music therapy; Group 2 ( ): Traditional social work interventions; Group 3 ( ): waitlist control groupMT & HPLAGS8 (60 m)84

Mood disorders and related psychopathology

Field, 1998 [43]USAAmbulatory care clinicParallel RCT28 Chronic depression14–19Group 1 : Music intervention (Rock music); Group 2 : Self-relaxation interventionRRPOS1 (23 m) 13

Wooten, 1992 [44]USAInpatient psychiatric facilityCrossover RCT35 (14)Psychopathology (affective, behavior, or substance abuse)12–18Group 1 : Music intervention (1980s heavy metal music + 1980s popular music); Group 2 : reversed order. Both groups began in baseline (reading material)RRPOS2 (20 m) 13

Acute and/or chronic physical illness

Colwell, 2005 [45]USAIn-patientParallel RCT24 (15)Acute or chronic illness ( 75% oncology)7–18Group 1 : Art (drawing) composition group; Group 2 : Music (computerized instrumental) composition groupMTLAOI1 (45–60 m) 13
Robb, 2008 [46]USAIn-patientParallel RCT83 (n/a)Chronic illness (100% oncology)4–7Group 1 : Active music engagement (AME); Group 2 : Music listening (ML) and Group 3 ; Audio storybooks (ASB) formed two control groupsMT & HPL & RA & POS1 (15–20 m) 13

Froehlich, 1984 [47]USAIn-patientParallel RCT39 (22)Acute or chronic illness5–12Group 1 : Music therapy (instrumental and song based activities); Group 2 : Medical play therapy (storybook & free play)HPLAOS1 (30 m)<14

Grasso, 2000 [48]AustraliaAmbulatory care clinicParallel RCT21 (10)Cystic fibrosis0.38–2Group 1 : Unfamiliar instrumental treatment for 2 blocks; Group 2 : No music (Block 1; control) and familiar children's music (Block 2; placebo). Both groups received routine chest physiotherapy.MTRPOS42–168 (30 m)125
Oelkers-Ax, 2008 [49]GermanyCommunityParallel RCT58 (40)MigraineMean = 108-week baseline condition; Group 1 : Butterbur root extract; Group 2 : Music therapy (adaptation of the Heidleberg model); Group 3 : PlaceboMTLAOS12 (n/a)286

RCT: Randomized controlled trial.
MT: Music therapist; R: Researcher; HP: Health professional.
R: Prerecorded music; L: Live music.
A: Active involvement of participant (e.g., instrumental improvisation, song learning and signing, etc); P: Passive presentation to participant (e.g., listening).
G: Sessions offered to group; O: Sessions offered one-to-one.
S: Standardized intervention; I: Individualised intervention.