Biological Activities of Chinese Propolis and Brazilian Propolis on Streptozotocin-Induced Type 1 Diabetes Mellitus in Rats
Table 1
Protection against STZ-induced renal damage.
Group
Model
Chinese
Brazilian
Positive
Normal
KW (g)
3.10 ± 0.30
3.31 ± 0.17
3.24 ± 0.22
3.18 ± 0.43
2.54 ± 0.21**
KW/BW (‰)
11.91 ± 0.72
10.74 ± 0.67*
11.24 ± 0.76
10.38 ± 1.55**
5.68 ± 0.43**
BUN (mmol L–1)
14.19 ± 2.41
12.66 ± 3.59
9.23 ± 1.89**
10.50 ± 3.02**
4.14 ± 0.70**
SCr (umol L–1)
57.75 ± 3.33
56.25 ± 4.23
56.25 ± 3.41
59.25 ± 3.96
57.25 ± 5.42
UAER (mg/24 h)
0.45 ± 0.21
0.27 ± 0.16*
0.26 ± 0.18*
0.19 ± 0.13**
0.12 ± 0.05**
CCR (mL min–1)
2.02 ± 0.53
1.97 ± 0.25
1.97 ± 0.29
1.08 ± 0.54**
0.81 ± 0.43**
Values represent the mean ± SD, n = 8. KW, kidney weight; BW, body weight; BUN, blood urea nitrogen; SCr, serum creatinine; UAER, urinary albumin-excretion rate; CCR, creatinine clearance rate.
*
P < .05 and **P < .01, compared with the model group.
