Anti-Atherogenic Activity of Ethanolic Fraction of Terminalia arjuna Bark on Hypercholesterolemic Rabbits

Table 2

Serum lipid profile and atherogenic index.

No. of days	Parameters	Control	D. Control	Std	EtOH 100 (mg kg^−1)	EtOH 200 (mg kg^−1)
Baseline
	TC (mg dl^−1)	54.02 ± 1.99	53.42 ± 3.66	55.84 ± 3.44	54.91 ± 4.50	54.38 ± 3.04
	HDL (mg dl^−1)	31.69 ± 1.95	30.03 ± 1.15	29.47 ± 1.50	26.62 ± 1.88	30.62 ± 2.16
	LDL (mg dl^−1)	7.50 ± 3.41	5.86 ± 3.89	10.93 ± 3.62	14.13 ± 4.54	9.64 ± 2.06
	VLDL (mg dl^−1)	14.83 ± 0.73	17.53 ± 0.48	15.44 ± 0.77	14.16 ± 0.66	14.12 ± 0.82
	TG (mg dl^−1)	74.15 ± 3.65	87.63 ± 2.42	77.18 ± 3.85	70.80 ± 3.31	70.62 ± 4.11
14 days
	TC (mg dl^−1)	63.63 ± 4.95	143.36 ± 8.01(a)	71.82 ± 5.30(b)	122.90 ± 8.18(a),(b),(c)	108.76 ± 6.67(b),(c),(d)
	HDL (mg dl^−1)	35.13 ± 1.98	34.75 ± 4.27	38.25 ± 4.35	38.44 ± 1.62	40.50 ± 2.65
	LDL (mg dl^−1)	7.09 ± 7.09	15.86 ± 12.92	6.14 ± 5.68	15.73 ± 4.36	13.69 ± 9.78
	VLDL (mg dl^−1)	35.59 ± 1.66	92.75 ± 12.67(a)	39.70 ± 1.62(b)	68.73 ± 3.90(a),(b),(c)	51.95 ± 5.70(a),(b),(d)
	TG (mg dl^−1)	177.93 ± 8.29	463.77 ± 63.37(a)	198.50 ± 8.10(b)	373.63 ± 19.48(a),(b),(c)	299.76 ± 28.49(a),(b),(d)
36 days
	TC (mg dl^−1)	254.86 ± 2.18	552.55 ± 42.00(a)	269.83 ± 11.45(b)	399.96 ± 41.61(a),(b),(c)	359.65 ± 41.08(a),(b),(c)
	HDL (mg dl^−1)	33.94 ± 2.21	32.94 ± 3.56	38.00 ± 5.89	34.00 ± 4.40	37.91 ± 1.64
	LDL (mg dl^−1)	170.49 ± 5.41	347.48 ± 32.80(a)	175.53 ± 9.05(b)	177.33 ± 39.96(b)	208.64 ± 42.99(b)
	VLDL (mg dl^−1)	50.43 ± 6.57	172.13 ± 12.35(a)	56.29 ± 1.79(b)	138.63 ± 3.72(b)	113.10 ± 6.71(a),(b),(c),(d)
	TG (mg dl^−1)	252.15 ± 32.84	860.65 ± 61.77(a)	281.46 ± 8.96(b)	663.16 ± 18.58(a),(b),(c)	539.50 ± 33.55(a),(b),(c),(d)
72 days
	TC (mg dl^−1)	353.78 ± 5.78	868.43 ± 47.98(a)	384.69 ± 4.94(b)	604.58 ± 27.42(a),(b),(c)	543.47 ± 53.91(a),(b),(c),(d)
	HDL (mg dl^−1)	34.25 ± 1.71	30.00 ± 1.15	41.75 ± 4.92(b)	35.25 ± 2.99	38.58 ± 4.38(b)
	LDL (mg dl^−1)	252.41 ± 7.47	582.44 ± 52.37(a)	267.06 ± 2.23(b)	489.17 ± 33.85(a),(b),(c)	348.02 ± 63.85(a),(b),(d)
	VLDL (mg dl^−1)	67.11 ± 3.45	255.98 ± 7.82(a)	75.88 ± 2.25(b)	180.16 ± 13.48(a),(b),(c)	156.87 ± 9.58(a),(b),(c),(d)
	TG (mg dl^−1)	335.57 ± 17.27	1279.92 ± 39.09(a)	379.38 ± 11.23(b)	900.79 ± 67.40(a),(b),(c)	704.36 ± 47.92(a),(b),(c),(d)
	Atherogenic Index	10.32 ± 2.38	28.94 ± 2.55	9.21 ± 1.02	19.98 ± 4.18	14.08 ± 3.31

Values expressed are mean ± SD of four animals per group.
(a),(b),(c),(d)statistical significance at P < .05 when compared with control, disease control, standard and treatment, respectively, on performing repeated measures ANOVA with Tukey’s multiple comparison post hoc test.