Antimetastatic Potentials of Dioscorea nipponica on Melanoma In Vitro and In Vivo
Figure 8
The effects of DNE3 on cell motility, invasion, and the activity of MMPs and uPA of A2058 human melanoma cells. Cells were treated with DNE3 for 24 hours and then subjected to analyze for motility ((a) and (c)) and invasion ((b) and (d)). Condition media were subjected to gelatin zymography and casein zymography to analyze the activities of MMPs (e) and u-PA (f), respectively. Data represented the of at least 3 independent experiments. Results were statistically evaluated by using one-way ANOVA with post hoc Dunnett's test (*; **; ***).
