Attenuation of Diabetic Nephropathy in Otsuka Long-Evans Tokushima Fatty (OLETF) Rats with a Combination of Chinese Herbs (Tangshen Formula)

Table 1

Rheological parameters in control and Tangshen Formula treated rats.

	36 weeks of age			56 weeks of age
Groups	Whole blood	Whole blood	Plasma	Whole blood	Whole blood	Plasma
	viscosity	viscosity	viscosity	viscosity	viscosity	viscosity
	(0.945 s) (mPa⋅S)	(94.5 s) (mPa⋅S)	(mPa⋅ S)	(0.945 s) (mPa⋅S)	(94.5 s) (mPa⋅S)	(mPa⋅S)
LETO	4.45±0.14	17.90±1.18	1.29±0.03 **	4.37±0.14 **	18.42±1.04 **	1.31±0.03 **
OLETF	4.67±0.12	16.78±0.87	1.42±0.03	5.56±0.15^##	26.97±1.38^##	1.51±0.06
OLETF + TSF	4.74±0.28	14.05±0.74	1.33±0.02 **	4.85±0.06 *	20.96±2.22^*##	1.35±0.05 *
OLETF + Monopril	4.67±0.14	14.58±1.00	1.37±0.02	5.64±0.38^#	26.61±1.10^##	1.40±0.05

Data represent mean ± SEM; *𝑃<.05, **𝑃<.01 versus control OLETF rats; ^#𝑃<.05, ^##𝑃<.01 compares the 36 and 56 weeks of age data groups.