Biochanin A, a Phytoestrogenic Isoflavone with Selective Inhibition of Phosphodiesterase 4, Suppresses Ovalbumin-Induced Airway Hyperresponsiveness
Figure 2
Effects of biochanin A (30~100 μmol/kg, p.o.) on (a) and (b) in sensitized mice receiving aerosolized methacholine (MCh, 0.78~25 mg/mL) 2 days after primary allergen challenge. ##, and ###, compared to the nonchallenged group. ***, compared to the control (vehicle) group. The number of mice in each group was 10. PBS: phosphate-buffered saline.
