Biochanin A, a Phytoestrogenic Isoflavone with Selective Inhibition of Phosphodiesterase 4, Suppresses Ovalbumin-Induced Airway Hyperresponsiveness
Figure 5
Effects of subcutaneously administered (a) biochanin A and Ro 20-1724 (b) on the duration of xylazine (10 mg/kg, i.p.)/ketamine (70 mg/kg, i.p.)-induced anesthesia in mice. Biochanin A or Ro 20-1724 was administered 15 min or 1 h prior to anesthesia, respectively. ***, compared to the vehicle (control). Each value represents the mean ± SEM. The numbers of mice used for biochanin A and Ro 20-1724 were 14 and 21, respectively.