Research Article

Biochanin A, a Phytoestrogenic Isoflavone with Selective Inhibition of Phosphodiesterase 4, Suppresses Ovalbumin-Induced Airway Hyperresponsiveness

Figure 5

Effects of subcutaneously administered (a) biochanin A and Ro 20-1724 (b) on the duration of xylazine (10 mg/kg, i.p.)/ketamine (70 mg/kg, i.p.)-induced anesthesia in mice. Biochanin A or Ro 20-1724 was administered 15 min or 1 h prior to anesthesia, respectively. *** , compared to the vehicle (control). Each value represents the mean ± SEM. The numbers of mice used for biochanin A and Ro 20-1724 were 14 and 21, respectively.
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(a)
635058.fig.005b
(b)