Biochanin A, a Phytoestrogenic Isoflavone with Selective Inhibition of Phosphodiesterase 4, Suppresses Ovalbumin-Induced Airway Hyperresponsiveness

<table>Effects of biochanin A (a) and Ro 20-1724 (b) on cumulative ovalbumin (OVA)-induced contractions in isolated sensitized guinea pig trachealis. *<svg height="11.375" id="M95" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 50.549999 11.375" width="50.549999" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>, and ***<svg height="11.375" id="M97" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>, compared to the control (vehicle). Each value represents the mean ± SEM (<svg height="11.125" id="M98" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 63.825001 11.125" width="63.825001" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>).</table>

Evidence-Based Complementary and Alternative Medicine

fig6

Figure 6

Figure 6: Biochanin A, a Phytoestrogenic Isoflavone with Selective Inhibition of Phosphodiesterase 4, Suppresses Ovalbumin-Induced Airway Hyperresponsiveness 

Figure 6 | Biochanin A, a Phytoestrogenic Isoflavone with Selective Inhibition of Phosphodiesterase 4, Suppresses Ovalbumin-Induced Airway Hyperresponsiveness 