Antioxidant and Hepatoprotective Effects of Silibinin in a Rat Model of Nonalcoholic Steatohepatitis

<table>Pathogenesis of NASH and major action fields of the Silibinin treatment. Main results-defined pathological pathway leading to NASH and key action points of Silibinin in the liver to reverse the disease's development. mito, mitochondria; HNE, <i>trans</i>-4-hydroxy-2-nonenal; VLDL, very low density lipoproteins; arrow: induces; blunt arrow: inhibits; plus: increases; minus: decreases.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 7

Figure 7: Antioxidant and Hepatoprotective Effects of Silibinin in a Rat Model of Nonalcoholic Steatohepatitis 