Dioscorea Phytocompounds Enhance Murine Splenocyte Proliferation Ex Vivo and Improve Regeneration of Bone Marrow Cells In Vivo
Figure 3
Fractionated tissue extracts of Dioscorea tuber effectively help to regenerate or recover test cells of bone marrow and spleen tissues of 5-FU-treated BALB/c mice. Mice were pre-treated with 5-FU at 100 mg kg−1 body weight; 24 h later, test mice (three mice per group) were force-fed for five consecutive days with 0 or 10 mg kg−1 body weight of D. batatas Decne tuber extracts (DsCE-I or DsCE-II). Experimental data are expressed as mean ± SD. Filled squares indicate BMCs; open squares depict splenocytes. Significant difference (*) when compared with 5-FU treatment control. An independent experiment was repeated and similar results obtained.
