Black Cohosh Hepatic Safety: Follow-Up of 107 Patients Consuming a Special Cimicifuga racemosa rhizome Herbal Extract and Review of Literature

Table 3

Follow up of five patients suffering from stable chronic liver disease.

Patients at baseline and control	1 Baseline	1 Control	2 Baseline	2 Control	3 Baseline	3 Control	4 Baseline	4 Control	5 Baseline	5 Control
Leukocyte	5780 mm^3	6300 mm^3	3990 mm^3	4100 mm^3	6700 mm^3	6900 mm^3	8000 mm^3	7450 mm^3	3450 mm^3	4500 mm^3
Tot bilirubin	1.4 mg dl^−1	1.3 mg dl^−1	0.9 mg dl^−1	0.9 mg dl^−1	0.7 mg dl^−1	0.6 mg dl^−1	0.2 mg dl^−1	0.3 mg dl^−1	0.4 mg dl^−1	0.5 mg dl^−1
AST	57 IU l^−1	67 IU l^−1	38 IU l^−1	39 IU l^−1	45 IU l^−1	46 IU l^−1	38 IU l^−1	42 IU l^−1	41 IU l^−1	33 IU l^−1
ALT	47 IU l^−1	52 IU l^−1	36 IU l^−1	33 IU l^−1	37 IU l^−1	35 IU l^−1	20 IU l^−1	18 IU l^−1	45 IU l^−1	42 IU l^−1
Alkaline phosphatase	150 U l^−1	156 U l^−1	119 U l^−1	118 U l^−1	110 U l^−1	105 U l^−1	120 U l^−1	122 U l^−1	110 U l^−1	80 U l^−1
γGT	55 U l^−1	59 U l^−1	22 U l^−1	25 U l^−1	35 U l^−1	32 U l^−1	45 U l^−1	44 U l^−1	48 U l^−1	35 U l^−1
Albumin	3.5 g dl^−1	3.6 g dl^−1	4.1 g dl^−1	4.2 g dl^−1	3 g dl^−1	2.9 g dl^−1	3.8 g dl^−1	4 g dl^−1	4.2 g dl^−1	4.4 g dl^−1
INR	0.8	0.9	1.2	1.3	0.9	0.9	1.1	1.1	1	1.2