Treatment of Rheumatoid Arthritis with Marine and Botanical Oils: Influence on Serum Lipids
Table 3
(a) Serum Lipids and Atherogenic Index of Plasma
Baseline mean (SD) ()
Change from baseline to 9 months ()
Change from baseline to 18 months ()
Total cholesterol
195.77 (37.48)
−3.45 (−7.88 to 0.98)
−8.43* (−12.99 to −3.86)
LDL
114.63 (32.20)
−4.39** (−8.03 to −0.74)
−9.43* (−13.75 to −5.11)
HDL
54.14 (16.21)
3.96* (2.44 to 5.49)
5.02* (3.24 to 6.81)
TC/HDL ratio†
3.83 (1.03)
−0.26* (−0.41 to −0.12)
−0.43* (−0.58 to −0.28)
Triglyceride†
138.05 (79.65)
−21.96* (−30.52 to −13.40)
−24.42* (−33.22 to −15.61)
Atherogenic index of plasma
0.84 (0.67)
−0.22* (−0.29 to −0.16)
−0.26* (−0.33 to −0.19)
Values are presented as regression coefficient (95% CI) unless stated otherwise and control from baseline values. * ** † value are from log-transformed data.
(b) Triglycerides and atherogenic index of plasma (AIP) by group
Combination group
Fish oil group
Borage oil group
value
Triglyceride**
0.031
9 months
−30.81 (−46.58 to −15.03)
−20.50 (−35.16 to −5.85)
−16.57 (−30.86 to −2.27)
18 months
−38.24 (−54.28 to −22.19)
−15.27 (−29.81 to −0.74)
−22.10 (−37.32 to −6.89)
AIP
0.011
9 months
−0.33 (−0.45 to −0.20)
−0.20 (−0.32 to −0.08)
−0.17 (−0.33 to 0.002)
18 months
−0.45 (−0.57 to −0.32)
−0.16 (−0.28 to −0.05)
−0.21 (−0.33 to −0.09)
**
value is from log transformation. Changes shown are from the original scale for the group × time interaction and control for baseline values. Values are presented as regression coefficient (95% CI).
