Research Article

Antitumor and HIV-1 Reverse Transcriptase Inhibitory Activities of a Hemagglutinin and a Protease Inhibitor from Mini-Black Soybean

Table 5

Comparison of lectins from different cultivars of soybean.

Soybean lectinChinese mini-black soybean hemagglutinin

Molecular weight122 kDa25 kDa
No. of subunits41
Sugar specificityN-acetylgalactosamineD(+)-raffinose
pH stabilitypH 2–13pH 2–13
ThermostabilityUp to 50°CUp to 75°C
Antitumor activityPresentHepG2 IC50: 6.2 μM
MCF-7 IC50: 3.5 μM
Inhibitory activity of HIV-1 reverse transcriptasePresentIC50: 5.5 μM