Antitumor and HIV-1 Reverse Transcriptase Inhibitory Activities of a Hemagglutinin and a Protease Inhibitor from Mini-Black Soybean

Table 6

Comparison of trypsin inhibitors from different cultivars of soybean.

	Soybean trypsin inhibitor	Chinese mini-black soybean Protease inhibitor
Molecular weight	20 kDa	17.5 kDa
Monomeric/with subunits	Monomeric	Monomeric
pH stability	pH 3–13	pH 2–13
Thermostability	Not done	Up to 70°C
Trypsin inhibitory activity	IC50: 7.2 μM	IC50: 8.8 μM
Chymotrypsin inhibitory activity	IC50: 7.6 μM	IC50: 7.9 μM
Inhibition of trypsin inhibitor by DTT (IC50)	Lower than 10 mM	30 mM