Bioactivity of the Murex Homeopathic Remedy and of Extracts from an Australian Muricid Mollusc against Human Cancer Cells

Figure 7

Chloroform extracts from D. orbita egg masses contain at least two brominated indoles with anti-cancer activity that can be purified by silica chromotography. The orange fraction contains tyrindoleninone, which is predicted to induce apoptosis in lymphoma cells, whereas the more polar yellow compound is the cytotoxin 6-bromoisatin, which causes necrosis in lymphoma and solid tumor cell lines.