Antinociceptive Activities and the Mechanisms of Anti-Inflammation of Asiatic Acid in Mice
Figure 6
Effects of AA and Indo on Carr-induced (a) NO, (b) TNF-α, and (c) interlukin-1β concentrations of serum at the 5th h in mice. Normal control received 0.9% normal saline. Animals treated with AA (1, 5, and 10 mg/kg) and Indo were assayed in the right hind paws. After 5 h, the animals were sacrificed and blood was withdrawn. Then fresh blood was centrifuged, and the supernatant was obtained for measuring NO, TNF-α, and interlukin-1β levels. Each value represents as mean ± S.E.M. ### as compared with the control group. *, **, and *** as compared with the Carr group (one-way ANOVA followed by Scheffé’s multiple range test).
