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Evidence-Based Complementary and Alternative Medicine
Volume 2011 (2011), Article ID 908059, 7 pages
http://dx.doi.org/10.1093/ecam/neq026
Original Article

Analysis of the Potential Topical Anti-Inflammatory Activity of Averrhoa carambola L. in Mice

1Laboratory of Inflammation, Department of Pharmacology, Universidade Federal do Paraná, Curitiba, PR, Brazil
2Department of Chemistry, Universidade Federal de Santa Catarina, Campus Universitário, Trindade, Florianópolis, SC, Brazil
3Department of Pharmaceutical Sciences, Universidade Estadual de Ponta Grossa, Ponta Grossa, Campus Uvaranas, Av. General Carlos Cavalcanti 4748, Bloco M, Sala 94, 84030-900, PR, Brazil

Received 15 October 2009; Accepted 8 March 2010

Copyright © 2011 Daniela Almeida Cabrini et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. T. Welss, D. A. Basketter, and K. R. Schröder, “In vitro skin irritation: facts and future. State of the art review of mechanisms and models,” Toxicology in Vitro, vol. 18, no. 3, pp. 231–243, 2004. View at Publisher · View at Google Scholar · View at PubMed
  2. E. Proksch, J. M. Brandner, and J.-M. Jensen, “The skin: an indispensable barrier,” Experimental Dermatology, vol. 17, no. 12, pp. 1063–1072, 2008. View at Publisher · View at Google Scholar
  3. C. DeBenedictis, S. Joubeh, G. Zhang, M. Barria, and R. F. Ghohestani, “Immune functions of the skin,” Clinics in Dermatology, vol. 19, no. 5, pp. 573–585, 2001. View at Publisher · View at Google Scholar
  4. E. F. Pietrovski, M. D. A. Magina, F. Gomig et al., “Topical anti-inflammatory activity of Eugenia brasiliensis Lam. (Myrtaceae) leaves,” Journal of Pharmacy and Pharmacology, vol. 60, no. 4, pp. 479–487, 2008. View at Publisher · View at Google Scholar · View at PubMed
  5. K. B. Gordon and E. M. Ruderman, “The treatment of psoriasis and psoriatic arthritis: an interdisciplinary approach,” Journal of the American Academy of Dermatology, vol. 54, no. 3, pp. S85–S91, 2006. View at Publisher · View at Google Scholar · View at PubMed
  6. E. Sonkoly, A. Muller, A. I. Lauerma et al., “IL-31: a new link between T cells and pruritus in atopic skin inflammation,” Journal of Allergy and Clinical Immunology, vol. 117, no. 2, pp. 411–417, 2006. View at Publisher · View at Google Scholar · View at PubMed
  7. A. Kumar, R. Prasad, N. M. Jogge, S. Bhojraj, S. F. Emerson, and S. Prabakar, “Herbex-kid inhibits immediate hypersensitivity reactions in mice and rats,” Evidence-Based Complementary and Alternative Medicine, vol. 5, no. 3, pp. 289–294, 2008. View at Publisher · View at Google Scholar · View at PubMed
  8. G. A. Cordell and M. D. Colvard, “Some thoughts on the future of ethnopharmacology,” Journal of Ethnopharmacology, vol. 100, no. 1-2, pp. 5–14, 2005. View at Publisher · View at Google Scholar · View at PubMed
  9. H. Kobayashi, M. Ishii, S. Takeuchi et al., “Efficacy and safety of a traditional herbal medicine, hochu-ekki-to in the long-term management of Kikyo (Delicate Constitution) patients with atopic dermatitis: a 6-month, multicenter, double-blind, randomized, placebo-controlled study,” Evidence-Based Complementary and Alternative Medicine, vol. 7, no. 3, pp. 367–373, 2010. View at Publisher · View at Google Scholar · View at PubMed
  10. B. Padmavathi, P. C. Rath, A. R. Rao, and R. P. Singh, “Roots of Withania somnifera inhibit forestomach and skin carcinogenesis in mice,” Evidence-Based Complementary and Alternative Medicine, vol. 2, no. 1, pp. 99–105, 2005. View at Publisher · View at Google Scholar · View at PubMed
  11. R. O. G. Carolino, R. O. Beleboni, A. B. Pizzo et al., “Convulsant activity and neurochemical alterations induced by a fraction obtained from fruit Averrhoa carambola (Oxalidaceae: Geraniales),” Neurochemistry International, vol. 46, no. 7, pp. 523–531, 2005. View at Publisher · View at Google Scholar · View at PubMed
  12. P. M. Corrêa, Dicionário de plantas úteis do Brasil e das exóticas cultivadas, Imprensa Nacional, Rio de Janeiro, 1984.
  13. M. Provasi, C. E. Oliveira, M. C. Martino, L. G. Pessini, R. B. Bazotte, and D. A. G. Cortez, “Avaliação da toxicidade e do potencial antihiperglicemiante da Averrhoa carambola L. Oxalidaceae,” Acta Scientiarum, vol. 23, pp. 665–669, 2001.
  14. K. P. Tiwari, M. Masood, and P. K. Minocha, “Chemical constituents of Gemlina phillipinensis, Adenocalymna nitida, Allamanda cathartica, Averrhoa carambola and Maba buxifolia,” Journal of the Indian Chemical Society, vol. 56, p. 944, 1979.
  15. S. Ranganayaki, R. Singh, and A. K. Singh, “The chemical examination of the bark of Avehrroa carambola,” Proceedings of the National Academy of Sciences India Section A, vol. 50, pp. 61–63, 1980.
  16. R. Gunasegaran, “Flavonoids and anthocyanins of three oxalidaceae,” Fitoterapia, vol. 63, no. 1, pp. 89–90, 1992.
  17. S. H. Tadros and A. A. Sleem, “Pharmacognostical and biological study of the stem and leaf of Avehrroa carambola L,” Bulletin of Faculty of Pharmacy, vol. 42, pp. 225–246, 2004.
  18. D. Araho, M. Miyakoshi, W.-H. Chou, T. Kambara, K. Mizutani, and T. Ikeda, “A new flavone C-glycoside from the leaves of Avehrroa carambola,” Natural Medicines, vol. 59, no. 3, pp. 113–116, 2005.
  19. G. Shui and L. P. Leong, “Residue from star fruit as valuable source for functional food ingredients and antioxidant nutraceuticals,” Food Chemistry, vol. 97, no. 2, pp. 277–284, 2006. View at Publisher · View at Google Scholar
  20. C.-F. Chau, C.-H. Chen, and Y.-T. Wang, “Effects of a novel pomace fiber on lipid and cholesterol metabolism in the hamster,” Nutrition Research, vol. 24, no. 5, pp. 337–345, 2004. View at Publisher · View at Google Scholar
  21. C. Chau, C. Chen, and C. Lin, “Insoluble fiber-rich fractions derived from Averrhoa carambola: hypoglycemic effects determined by in vitro methods,” Lebenson Wiss Technology, vol. 37, pp. 331–335, 2004.
  22. R. Suzuki, Y. Okada, and T. Okuyama, “A new flavone C-glycoside from the Zea mays mays L. with glycation inhibitory activity,” Chemical and Pharmaceutical Bulletin, vol. 51, no. 10, pp. 1186–1188, 2003. View at Publisher · View at Google Scholar
  23. S. Rayyan, T. Fossen, and Ø. M. Andersen, “Flavone C-glycosides from leaves of Oxalis triangularis,” Journal of Agricultural and Food Chemistry, vol. 53, no. 26, pp. 10057–10060, 2005. View at Publisher · View at Google Scholar · View at PubMed
  24. M. F. Otuki, F. Vieira-Lima, Â. Malheiros, R. A. Yunes, and J. B. Calixto, “Topical antiinflammatory effects of the ether extract from Protium kleinii and α-amyrin pentacyclic triterpene,” European Journal of Pharmacology, vol. 507, no. 1–3, pp. 253–259, 2005. View at Publisher · View at Google Scholar · View at PubMed
  25. K. Suzuki, H. Ota, S. Sasagawa, T. Sakatani, and T. Fujikura, “Assay method for myeloperoxidase in human polymorphonuclear leukocytes,” Analytical Biochemistry, vol. 132, pp. 345–352, 1983.
  26. L. M. De Young, J. B. Kheifets, S. J. Ballaron, and J. M. Young, “Edema and cell infiltration in the phorbol ester-treated mouse ear are temporally separate and can be differentially modulated by pharmacologic agents,” Agents Actions, vol. 26, pp. 335–341, 1989.
  27. M. Gábor, Mouse Ear Inflammation Models and Their Pharmacological Applications, Akadémiai Kiadó, Budapest, Hungary, 2000.
  28. X. Wang, M. Lan, H.-P. Wu et al., “Direct effect of croton oil on intestinal epithelial cells and colonic smooth muscle cells,” World Journal of Gastroenterology, vol. 8, no. 1, pp. 103–107, 2002.
  29. S. Rahman, R. A. Ansari, H. Rehman, S. Parvez, and S. Raisuddin, “Nordihydroguaiaretic acid from Creosote bush (Larrea tridentata) mitigates 12-O-tetradecanoylphorbol-13-acetate-induced inflammatory and oxidative stress responses of tumor promotion cascade in mouse skin,” Evidence-Based Complementary and Alternative Medicine. In press. View at Publisher · View at Google Scholar · View at PubMed
  30. M. F. Denning, “Epidermal keratinocytes: regulation of multiple cell phenotypes by multiple protein kinase C isoforms,” International Journal of Biochemistry and Cell Biology, vol. 36, no. 7, pp. 1141–1146, 2004. View at Publisher · View at Google Scholar · View at PubMed
  31. M. Gábor, “Models of acute inflammation in the ear,” Methods in Molecular Biology, vol. 225, pp. 129–137, 2003.
  32. F. R. Stermitz, P. Lorenz, J. N. Tawara, L. A. Zenewicz, and K. Lewis, “Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5′-methoxyhydnocarpin, a multidrug pump inhibitor,” Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 4, pp. 1433–1437, 2000.
  33. T. Sánchez and J. J. Moreno, “Role of leukocyte influx in tissue prostaglandin H synthase-2 overexpression induced by phorbol ester and arachidonic acid in skin,” Biochemical Pharmacology, vol. 58, no. 5, pp. 877–879, 1999. View at Publisher · View at Google Scholar
  34. P. Schaerli, M. Britschgi, M. Keller et al., “Characterization of human T cells that regulate neutrophilic skin inflammation,” Journal of Immunology, vol. 173, no. 3, pp. 2151–2158, 2004.
  35. P. P. Bradley, D. A. Priebat, R. D. Christensen, and G. Rothstein, “Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker,” Journal of Investigative Dermatology, vol. 78, no. 3, pp. 206–209, 1982.
  36. K.-L. E. Hon, V. W. Y. Lee, T.-F. Leung et al., “Corticosteroids are not present in a traditional Chinese medicine formulation for atopic dermatitis in children,” Annals of the Academy of Medicine Singapore, vol. 35, no. 11, pp. 759–763, 2006.
  37. D. Y. M. Leung, M. Boguniewicz, M. D. Howell, I. Nomura, and Q. A. Hamid, “New insights into atopic dermatitis,” Journal of Clinical Investigation, vol. 113, no. 5, pp. 651–657, 2004. View at Publisher · View at Google Scholar
  38. V. S. C. Pua and R. St. C. Barnetson, “Recent developments in the treatment of adult atopic dermatitis,” Australasian Journal of Dermatology, vol. 47, no. 2, pp. 84–89, 2006. View at Publisher · View at Google Scholar · View at PubMed
  39. P. J. Mease and M. A. Menter, “Quality-of-life issues in psoriasis and psoriatic arthritis: outcome measures and therapies from a dermatological perspective,” Journal of the American Academy of Dermatology, vol. 54, no. 4, pp. 685–704, 2006. View at Publisher · View at Google Scholar · View at PubMed
  40. L. A. J. O'Neill, “Targeting signal transduction as a strategy to treat inflammatory diseases,” Nature Reviews Drug Discovery, vol. 5, no. 7, pp. 549–563, 2006. View at Publisher · View at Google Scholar · View at PubMed
  41. J. L. Ríos, M. C. Recio, J. M. Escandell, and I. Andújar, “Inhibition of transcription factors by plant-derived compounds and their implications in inflammation and cancer,” Current Pharmaceutical Design, vol. 15, no. 11, pp. 1212–1237, 2009. View at Publisher · View at Google Scholar