Effects of bacterial toxins and allergens on dendritic cell activation of cAMP induction of transmembrane signaling and its receptor ligand. Binding of c-Kit to its ligand SCF stimulates dendritic cells to secrete IL-6. IL-6 acts as a key factor in differentiation of T lymphocytes into Th2 and Th17 cells, which contribute to the development of allergic and autoimmune diseases. By inhibiting enhanced IL-6 production, CAM practitioners may prevent, slow down or reverse the development of allergic and inflammatory disorders.