Aqueous Extract from Hibiscus sabdariffa Linnaeus Ameliorate Diabetic Nephropathy via Regulating Oxidative Status and Akt/Bad/14-3-3γ in an Experimental Animal Model

Table 2

Antioxidant enzyme profiles and marker of oxidative stress in renal tissues of rats from the different study groups (mean ± SD).

	Normal	Buffer	STZ group	STZ + HSE	STZ + HSE
				(100 g kg^−1)	(400 g kg^−1)
MDA (M mg^−1 protein)	2.83 ± 0.78	3.32 ± 0.78	4.04 ± 0.51(a)	2.74 ± 0.72(d)	2.31 ± 0.43(d)
Catalase (Units mg^−1 protein)	11.21 ± 4.78	11.25 ± 5.22	6.11 ± 3.03(b)	24.97 ± 6.93(d)	34.00 ± 8.81(d)
GSH (ng mg^−1 protein)	9.28 ± 0.40	9.63 ± 0.33	6.80 ± 0.29(b)	6.28 ± 0.25	9.25 ± 0.54(d)

n = 5. (a)P < .05; (b)P < .01 significant differently from control group; (c)P < .05; (d)P < .01 significant differently from STZ group.