Ethanol Extract from Ampelopsis sinica Root Exerts Anti-Hepatitis B Virus Activity via Inhibition of p53 Pathway <i>In Vitro</i>

<table>The effect of EASR on cell signaling pathway activity <i>in vitro</i>. The HepG2 cells were transfected with various plasmids provided by PathDetect Cis-/Trans-Reporting Systems. In the experimental group, cells were treated with 40 <i>μ</i>g mL<sup>-1</sup> EASR for 48 h. And the control group was cultured without EASR treatment. The signaling pathway activities were determined by luciferase reporter assay. EASR inhibited the activity of p53 pathway significantly (<svg height="11.375" id="M19" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 50.549999 11.375" width="50.549999" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>). The data are presented as means ± SD (<svg height="11.125" id="M20" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.125" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> as compared with the control group.</table>

Evidence-Based Complementary and Alternative Medicine

fig6

Figure 6

Figure 6: Ethanol Extract from Ampelopsis sinica Root Exerts Anti-Hepatitis B Virus Activity via Inhibition of p53 Pathway <i>In Vitro</i> 

Evidence-Based Complementary and Alternative Medicine

Ethanol Extract from Ampelopsis sinica Root Exerts Anti-Hepatitis B Virus Activity via Inhibition of p53 Pathway In Vitro

Figure 6