Targeting PML-RARα and Oncogenic Signaling Pathways by Chinese Herbal Mixture Tien-Hsien Liquid in Acute Promyelocytic Leukemia NB4 Cells

Figure 5

Proposed mechanisms of THL- and its active fraction EAS5-induced G2/M arrest in NB4 cells. The arrow indicates promotion, and the T-shaped bar indicates repression. The data of THL are presented in Figures 3, 4 and Table 1, and the data of EAS5 are presented in Figure 11 and Table 2.