Targeting PML-RARα and Oncogenic Signaling Pathways by Chinese Herbal Mixture Tien-Hsien Liquid in Acute Promyelocytic Leukemia NB4 Cells

Table 2

Effects of EAS5 on the cell-cycle distribution of NB4 cells.

Treatment (μg mL^−1)	Cell-cycle distribution
	Gl (%)	S (%)	G2/M (%)
PBS	56.93	28.62	14.44
EAS5 3.75	55.58	21.08	23.07
EAS5 7.5	48.76	29.60	21.64
EAS5 15	40.74	17.78	41.75
EAS5 30	41.63	14.22	44.14

The cell-cycle distributions of EAS5-treated NB4 cells in Figure 10(a) were listed in the Table. Like THL, EAS5 also induced G2/M arrest in NB4 cells. EAS5, active fraction of THL; THL, Tien-Hsien Liquid.