Anti-Inflammatory Activity Is a Possible Mechanism by Which the Polyherbal Formulation Comprised of Nigella sativa (Seeds), Hemidesmus indicus (Root), and Smilax glabra (Rhizome) Mediates Its Antihepatocarcinogenic Effects

Figure 6

Effect of the decoction on hepatic TNFα and IL-6 expression of C3H mice-bearing DEN induced early hepatocarcinogenic changes. Gene expression has quantified using scanning densitometry. Graph illustrates the mRNA expression of TNFα and IL-6 of each experimental group relative to expression of GAPDH house-keeping gene. Values are expressed as mean ± SEM (𝑛=8). ^∗𝑃<0.05 compared to distilled water control (DWC) and ^∗∗𝑃<0.05 compared to positive control (DEN) (ANOVA followed by Bonferroni’s posttest).