Understanding the Molecular Mechanism of Interventions in Treating Rheumatoid Arthritis Patients with Corresponding Traditional Chinese Medicine Patterns Based on Bioinformatics Approach
Figure 1
The responsive rates of biomedicine therapy and TCM therapy in treating RA patients with TCM cold and hot patterns. (a) shows two latent classes obtained. Class 1 includes less probability of fever, feverish joints, lassitude, thirst, red tongue, yellow tongue fur and turbid yellow colored urine, which is similar to the clinical manifestations of cold pattern. Class 2 shows higher frequency of those clinical manifestations, which is similar to clinical manifestations of hot pattern. (b) shows the ACR 20 responsive rates of TCM and biomedicine interventions in each latent class of patients. The responsive rate of TCM in RA patients with hot pattern was 72.09%, yet the corresponding rate of biomedicine was only 51.11% (). The responsive rate of TCM in RA patients with cold pattern was 51.06%, much lower than that of biomedicine therapy (82.61%, ).
