Involvement of Heme Oxygenase-1 Participates in Anti-Inflammatory and Analgesic Effects of Aqueous Extract of Hibiscus taiwanensis

Figure 2

Effects of AHT on lipopolysaccharide (LPS-) induced cell viability (a), NO (b), TNF-α (c), PGE₂ (d) productions, and iNOS, COX-2, and HO-1 expressions (e). Cells were incubated for 24 hrs with 100 ng/mL of LPS in the absence or presence of AHT (0, 62.5, 125, 250, 500, and 1,000 μg/mL). ARR was added 1 h before incubation with LPS. The data were presented as mean ± S.D. for three different experiments performed in triplicate. ^###Compared with sample of control group. *𝑃<0.05, **𝑃<0.01, and ***𝑃<0.001 were compared with LPS-alone group.

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