Involvement of Heme Oxygenase-1 Participates in Anti-Inflammatory and Analgesic Effects of Aqueous Extract of Hibiscus taiwanensis

Table 1

Effects of AHT and indomethacin (Indo) on changes in CAT, SOD, and GPx activities were studied on Carr-induced mice paw edema (5th h).

Groups	CAT (U/mg protein)	SOD (U/mg protein)	GPx (U/mg protein)
Control	5.89 ± 0.15	24.87 ± 0.13	23.35 ± 0.16
Carr	2.28 ± 0.08^###	14.64 ± 0.25^###	13.64 ± 0.11^###
Carr + Indo (10 mg/kg)	5.06 ± 0.24^**	22.17 ± 0.10^**	21.59 ± 0.19^**
Carr + AHT (0.25 g/kg)	3.19 ± 0.14	16.24 ± 0.16	15.78 ± 0.13
Carr + AHT (0.5 g/kg)	3.85 ± 0.09^*	19.49 ± 0.07^*	18.45 ± 0.18^*
Carr + AHT (1.0 g/kg)	5.17 ± 0.10^**	22.08 ± 0.18^**	20.96 ± 0.23^**

^*The values are averaged and obtained in individual animals (𝑛=6). Each value represents as mean ± S.E.M. ^###𝑃<0.001 as compared with the control group. ^*𝑃<0.05 and ^**𝑃<0.01 as compared with the Carr (𝜆-carrageenan) group (one-way ANOVA followed by Scheffe’s multiple range test).