(a)

(b)

(c)

(d)

(e)

(f)

Figure 4: Histopathological examinations on λ-carrageenan-induced paw tissue swelling, edema and neutrophil infiltration (a: epidermis, b: connective tissue, c: muscle fibers): (a) normal, (b) λ-carrageenan, (c) indomethacin, (d) CRMeOH (20 mg/kg), (e) CRMeOH (100 mg/kg), (f) CRMeOH (500 mg/kg). More swelling of the connective tissue, the distance is greater of the gap.