Table 1: Effect of CRMeOH and indomethacin on MDA, NO, TNF-α, IL-1β, IL-6, and NFκB level in the edema paws.

GroupsMDA
(nmol/mg protein)
NO (μM)TNF-α (pg/mg protein)IL-1β (ng/mg protein)IL-6 (ng/mg protein)NFκB (ng/mg protein)

Carr2.619 ± 0.1639.956 ± 0.437297.600 ± 15.539929.167 ± 60.5851483.900 ± 80.2190.842 ± 0.088
Carr + Indomethacin1.376 ± 0.096***6.438 ± 0.321***190.000 ± 11.779***639.500 ± 14.040*1113.500 ± 74.330*0.527 ± 0.032**
Carr + CRMeOH (20 mg/kg)2.328 ± 0.1497.699 ± 0.398*250.000 ± 16.441922.000 ± 76.0331239.000 ± 70.8250.538 ± 0.039**
Carr + CRMeOH (100 mg/kg)2.001 ± 0.187*6.918 ± 0.318***212.000 ± 8.569**740.000 ± 35.4071022.400 ± 89.513**0.516 ± 0.042***
Carr + CRMeOH (500 mg/kg)1.274 ± 0.065***6.222 ± 0.501***191.917 ± 9.339***606.000 ± 50.212**978.444 ± 44.539***0.493 ± 0.014***

Each value represents the mean ± S.E.M. (n = 8). *P < 0.05, **P < 0.01, and ***P < 0.001 as compared with the λ-carrageenan (Carr) group (one-way ANOVA followed by Scheffe’s multiple range test).