Table 2: Effect of CRMeOH and indomethacin on COX concentrations in mouse paw edema.

Groups COX-1 (U/mL/mg protein) COX-2 (U/mL/mg protein) Carr 133.588 ± 5.583 207.273 ± 9.984 Carr + Indomethacin 90.850 ± 2.963*** 135.669 ±7.489*** Carr + CRMeOH (20 mg/kg) 133.188 ± 6.656 162.505 ± 12.750 Carr + CRMeOH (100 mg/kg) 132.383 ± 7.511 148.923 ± 14.681* Carr + CRMeOH (500 mg/kg) 129.140 ± 5.214 134.936 ± 9.918***

Each value represents the mean ± S.E.M. (n = 8). *P < 0.05 and ***P < 0.001 as compared with the λ-carrageenan (Carr) group (one-way ANOVA followed by Scheffe’s multiple range test).