Bioassay-Guided Isolation and HPLC Determination of Bioactive Compound That Relate to the Antiplatelet Activity (Adhesion, Secretion, and Aggregation) from Solanum lycopersicum
Figure 3
Effect of aqueous extract and adenosine on collagen-induced platelet thrombus formation under arterial flow conditions. Citrate-anticoagulated blood was preincubated with aqueous extract (1 mg/mL), adenosine (114 μM), or negative control (saline 0.9%) for 1 hour and then was perfused over plaque-coated surfaces for 10 min at room temperature at a shear rate of 1000 s−1. (a) It shows the intensity (CTCF) over a time lapse, (b) bar diagram (values are mean ± SD; ), and (c) time lapse of 10 min at 1000 s−1, at 30 sec intervals. *.
