Effect of an Ethanol Extract of Scutellaria baicalensis on Relaxation in Corpus Cavernosum Smooth Muscle

Figure 4

(a) Comparison of ESB-induced cavernous smooth muscle relaxation in high K-contracted and PE-precontracted rabbit cavernosum smooth muscle strips. The mean value ± S.E. are shown. KCl 45 mM (𝑛=5), KCl + ESB (𝑛=5), PE + ESB (𝑛=7). *𝑃<0.001 versus PE + ESB. (b) Effects of K⁺ channel blockade on ESB-induced rabbit cavernous smooth muscle relaxation. TEA, tetraethylammonium; gliben, glibenclamide. (c) Effect of K⁺-selective inhibitor on ESB-induced rabbit cavernous smooth muscle relaxation. Mean values ± S.E. (𝑛=5) is shown. *𝑃<0.001 versus vehicle. (d) Effect of 4-aminopyridine (4-AP) on ESB-induced rabbit cavernous smooth muscle relaxation. Mean values ± S.E. (𝑛=4) are shown.

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