Mitigation of H<sub><b>2</b></sub>O<sub><b>2</b></sub>-Induced Mitochondrial-Mediated Apoptosis in NG108-15 Cells by Novel Mesuagenin C from <i>Mesua kunstleri</i> (King) Kosterm

<table>Mesuagenin C <b>3</b> modulated Bax and Bcl-2 protein expression in H<sub>2</sub>O<sub>2</sub>-treated NG108-15 cells. (a) Representative overlay of histograms showing Bax-associated immunofluorescence. (b) Bar chart represents dose-dependent downregulation of Bax protein expression after pretreatment with mesuagenin C <b>3</b>. (c) Representative overlay of histograms showing Bcl-2-associated immunofluorescence. (d) Bar chart represents dose-dependent elevation of Bcl-2 expression after pretreatment with mesuagenin C <b>3</b>. (e) Bar chart represents dose-dependent attenuation of Bax/Bcl-2 ratio. Values are mean ± S.E. from at least three independent experiments. The asterisk indicated significantly different values from H<sub>2</sub>O<sub>2</sub>-treated cells (*<svg height="11.375" id="M107" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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Evidence-Based Complementary and Alternative Medicine

fig9

Figure 9

Figure 9: Mitigation of H<sub><b>2</b></sub>O<sub><b>2</b></sub>-Induced Mitochondrial-Mediated Apoptosis in NG108-15 Cells by Novel Mesuagenin C from <i>Mesua kunstleri</i> (King) Kosterm 

Evidence-Based Complementary and Alternative Medicine

Mitigation of H2O2-Induced Mitochondrial-Mediated Apoptosis in NG108-15 Cells by Novel Mesuagenin C from Mesua kunstleri (King) Kosterm

Figure 9

Mitigation of H₂O₂-Induced Mitochondrial-Mediated Apoptosis in NG108-15 Cells by Novel Mesuagenin C from Mesua kunstleri (King) Kosterm