Research Article
Mitigation of H2O2-Induced Mitochondrial-Mediated Apoptosis in NG108-15 Cells by Novel Mesuagenin C from Mesua kunstleri (King) Kosterm
Table 2
Neuroprotective effects of 4-phenylcoumarins (200 μM) isolated from hexane bark of M. kunstleri against H2O2-induced apoptosis in NG108-15 cells.
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The values shown are the means ± SE of at least three independent experiments. aNG108-15 cells were pretreated with 4-phenylcoumarins (3.125–200 μM) for 2 h prior to exposure to H2O2 (2 mM). After incubation, cells were assessed by MTT to determine the percentage viability. bCell viability was measured by MTT assay. cH2O2-treated value differed significantly from the untreated control at the level of . dEGCG was used as standard positive control. #Results differ significantly from H2O2-treated group compared to the control untreated group: . *Significantly from H2O2-treated group compared to the treatment group: . |