Salvianolic Acid B Attenuates Rat Hepatic Fibrosis via Downregulating Angiotensin II Signaling

Figure 1

Effects of Sal B and perindopril (PER) on DMN-induced rat hepatic fibrosis. (a) Representative photomicrographs of Sirius red staining for rat liver. (b) western blot analysis of Col-I in rat liver. Rat liver protein was extracted and the samples were electrophoresed and analyzed by Western blot with Col-I antibody. ((c) and (d)) Quantities for densitometric analysis of Col-I and α-SMA. Each bar represents the means ± S.D. of three rats assayed in triplicate. (e) Hydroxyproline content in normal and DMN-induced rats livers. **𝑃<0.01 versus normal; ^##𝑃<0.01 versus model.

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