Table 2: Effects of trigonelline on motor and sensory nerve conduction velocity and tail flick latency in diabetic rats.

GroupMotor nerve conduction velocity (m/s)Sensory nerve conduction velocity (m/s)Tail flick latency in cold immersion (s)Tail flick latency in hot immersion (s)

Control55.34 ± 5.9257.61 ± 6.8514.5 ± 1.014.2 ± 0.9
Diabetes35.04 ± 4.36*40.17 ± 4.03*5.2 ± 1.0*6.3 ± 0.7*
Diabetes + trigonelline49.74 ± 5.05##51.76 ± 4.82##12.4 ± 1.1##12.0 ± 1.3##
Diabetes + sitagliptin41.05 ± 5.27#47.68 ± 3.38##10.8 ± 0.8##10.7 ± 1.0##

Data are given as mean ± SD, n = 10. *P < 0.01, compared with control rats; #P < 0.05, ##P < 0.01, compared with diabetes rats.