Hepatoprotective Effects of Panus giganteus (Berk.) Corner against Thioacetamide- (TAA-) Induced Liver Injury in Rats
Table 3
Effects of different treatments on serum liver biomarkers of experimental rats.
Group
ALP (IU/L)
ALT (IU/L)
AST (IU/L)
GGT (IU/L)
Bilirubin (μmol/L)
Total protein (g/L)
Albumin (g/L)
Control (distilled water)
70.17 ± 5.62a
46.50 ± 3.04a
164.00 ± 14.68a
5.00 ± 0.26a
2.40 ± 0.20a
69.33 ± 0.92cd
13.50 ± 0.34b
Control (P. giganteus)
79.17 ± 6.87a
46.00 ± 1.59a
151.00 ± 3.42a
5.20 ± 0.40a
2.60 ± 0.20a
70.83 ± 0.79d
13.83 ± 0.17b
TAA control (200 mg/kg)
218.17 ± 5.47c
65.33 ± 0.67c
198.67 ± 0.21b
12.67 ± 1.87c
7.17 ± 0.83c
63.83 ± 0.48a
11.17 ± 0.40a
Silymarin (50 mg/kg) + TAA
207.00 ± 11.93c
56.33 ± 2.19b
182.00 ± 5.82ab
10.00 ± 0.52bc
5.20 ± 0.31b
65.50 ± 0.56ab
12.83 ± 0.48ab
Panus giganteus (0.5 g/kg) + TAA
165.67 ± 5.67b
55.17 ± 2.34b
174.00 ± 8.80ab
7.17 ± 0.91ab
5.00 ± 0.26b
67.00 ± 0.26bc
14.00 ± 0.68b
Panus giganteus (1 g/kg) + TAA
166.67 ± 9.19b
53.33 ± 0.80ab
164.00 ± 4.37a
6.83 ± 0.60ab
4.80 ± 0.16b
67.17 ± 0.60bc
13.83 ± 0.40b
Two month treatment; food and water ad libitum. All values are expressed as mean ± S.E.M.; . Means with different letters (a–d) were significantly different at the level . ALP: alkaline phosphatase; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transferase.