Long-Term Oral Administration of Capsicum baccatum Extracts Does Not Alter Behavioral, Hematological, and Metabolic Parameters in CF1 Mice
Table 1
Effects of C. baccatum extracts on body weight (g), the relative weight of visceral organs and tissues (g/100 g b.w.), and food consumption (g/day) after a 60-day study in mice (200 mg/kg, per os).
Parameters
Control
Ethanol
Butanol
Initial weight (g)
33.7 ± 5.72
33.3 ± 4.03
30.7 ± 3.72
Final weight (g)
44.2 ± 4.68
43.1 ± 2.68
43.4 ± 6.63
Weight gained (g)
10.5 ± 3.63
9.8 ± 2.52
12.7 ± 3.33
Weight gained (%)
31.2
29.4
41.4
Food intake (g)/day
9.5 ± 1.9
9.0 ± 1.7
11.0 ± 2.2
Relative epididymal fat pad weight (%)
1.50 ± 0.48
1.02 ± 0.31
1.18 ± 0.34
Relative retroperitoneal fat pad weight (%)
0.50 ± 0.29
0.26 ± 0.13
0.38 ± 0.20
Relative liver weight (%)
5.52 ± 0.29
4.86 ± 0.17*
5.94 ± 0.44
Relative kidney weight (%)
1.82 ± 0.18
1.79 ± 0.15
1.78 ± 0.15
Relative heart weight (%)
0.47 ± 0.02
0.46 ± 0.05
0.45 ± 0.04
Relative brain weight (%)
1.07 ± 0.08
1.13 ± 0.04
1.08 ± 0.10
Relative lung weight (%)
0.52 ± 0.07
0.56 ± 0.04
0.63 ± 0.11
Relative stomach weight (%)
0.73 ± 0.07
0.69 ± 0.26
0.84 ± 0.15
*Significant difference compared with the control (). Values are mean ± SEM of 10 animals.