Long-Term Oral Administration of Capsicum baccatum Extracts Does Not Alter Behavioral, Hematological, and Metabolic Parameters in CF1 Mice
Table 3
Serum biochemical evaluations of mice following gavage administration of C. baccatum extracts for 60 days (200 mg/kg).
Parameters
Control
Ethanol
Butanol
ALT (IU/L)
29.0 ± 10.94
45.8 ± 40.52
42.2 ± 18.79
ALP (IU/L)
45.7 ± 21.74
28.5 ± 15.93
41.3 ± 14.68
Proteins (mg/dL)
4.9 ± 0.58
4.9 ± 0.42
4.8 ± 0.38
Albumin (mg/dL)
2.0 ± 0.45
2.0 ± 0.21
1.6 ± 0.38
LDH (IU/L)
150.2 ± 37.2
202.2 ± 83.93
148.0 ± 22.43
Triglycerides (mg/dL)
91.0 ± 25.63
76.4 ± 21.97
102.2 ± 31.42
Cholesterol (mg/dL)
129.5 ± 9.93
101.0 ± 13.58
119.4 ± 26.81
HDL-cholesterol (mg/dL)
63.5 ± 8.68
53.3 ± 7.69
56.7 ± 10.08
LDL-cholesterol (mg/dL)
47.8 ± 11.28
32.4 ± 11.08
42.3 ± 24.55
Glucose (mg/dL)
96.2 ± 44.45
133.5 ± 47.53
108.6 ± 34.70
Urea (mg/dL)
42.5 ± 3.15
45.6 ± 1.52
45.3 ± 12.53
Creatinine (mg/dL)
<0.20
0.20 ± 0.04
<0.20
ALT: alanine aminotransferase; ALP: alkaline phosphatase; LDH: lactate dehydrogenase. Neither of the treated groups was significantly different from the control group. Values are means ± SEM of 10 animals. No significant difference was observed among groups ().