Network-Based Gene Expression Biomarkers for Cold and Heat Patterns of Rheumatoid Arthritis in Traditional Chinese Medicine

Table 6

The pathways related to the differently expressed genes between the heat pattern and control comparison.

KEGG pathway	Related genes	Ratio
hsa03040: Spliceosome	LSM6, HSPA1A, HSPA8	1.54, 1.43, 0.63
hsa04612: Antigen processing and presentation	HSPA1A, HSPA8	1.43, 0.63
hsa04144: Endocytosis	HSPA1A, HSPA8	1.43, 0.63
hsa04010: MAPK signaling pathway	HSPA1A, HSPA8	1.43, 0.63
hsa03018: RNA degradation	LSM6	1.54
hsa04640: Hematopoietic cell lineage	CD59	1.52
hsa04610: Complement and coagulation cascades	CD59	1.52
hsa04150: mTOR signaling pathway	PRKAA1	1.45
hsa04920: Adipocytokine signaling pathway	PRKAA1	1.45
hsa04140: Regulation of autophagy	PRKAA1	1.45
hsa05410: Hypertrophic cardiomyopathy (HCM)	PRKAA1	1.45
hsa04910: Insulin signaling pathway	PRKAA1	1.45
hsa05020: Prion diseases	HSPA1A	1.43
hsa05130: Pathogenic Escherichia coli infection	NCL	0.70