Research Article

Network-Based Gene Expression Biomarkers for Cold and Heat Patterns of Rheumatoid Arthritis in Traditional Chinese Medicine

Table 9

GO-discovered categories for the genes that differed between the heat pattern and the control.

GO IDGO nameNumber of genesP valueGene name

Biological process
 GO:0006950Response to stress50.0235CAMP, CD59, PRKAA1, HSPA1A, HSPA8
 GO:0009607Response to biotic stimulus30.0287CAMP, HSPA1A, HSPA8
 GO:0006986Response to unfolded protein20.0492HSPA1A, HSPA8
 GO:0051789Response to protein stimulus20.0733HSPA1A, HSPA8
Cellular constituent
 GO:0030529Ribonucleoprotein complex40.0076LSM6, HSPA1A, NCL, HSPA8
Molecular function
 GO:0000166Nucleotide binding50.0205ASCC3, PRKAA1, HSPA1A, NCL, HSPA8
 GO:0005524ATP binding40.0357ASCC3, PRKAA1, HSPA1A, HSPA8
 GO:0032559Adenyl ribonucleotide binding40.0369ASCC3, PRKAA1, HSPA1A, HSPA8
 GO:0030554Adenyl nucleotide binding40.0423ASCC3, PRKAA1, HSPA1A, HSPA8
 GO:0001883Purine nucleoside binding40.0440ASCC3, PRKAA1, HSPA1A, HSPA8
 GO:0001882Nucleoside binding40.0447ASCC3, PRKAA1, HSPA1A, HSPA8
 GO:0051082Unfolded protein binding20.0592HSPA1A, HSPA8
 GO:0032553Ribonucleotide binding40.0623ASCC3, PRKAA1, HSPA1A, HSPA8
 GO:0032555Purine ribonucleotide binding40.0623ASCC3, PRKAA1, HSPA1A, HSPA8
 GO:0017076Purine nucleotide binding40.0695ASCC3, PRKAA1, HSPA1A, HSPA8