In Vivo Study on the Pharmacological Interactions between a Chinese Herbal Formula ELP and Antiresorptive Drugs to Counteract Osteoporosis

Figure 4

Alterations in trabecular bone volume (BV/TV), trabecular number (Tb.N), trabecular thickness (Tb.Th), and trabecular separation (Tb.Sp) at the distal femur metaphysis following 8 weeks of treatment with different combinations of alendronate (a, c, e, and g) and raloxifene (b, d, f, and h). Bars represent the mean ± SEM for each treatment group (𝑛=8 per group). Significant difference: *𝑃<0.05; **𝑃<0.01 for difference from OVX group without treatment.

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