Hepatoprotective Activity of the Total Saponins from Actinidia valvata Dunn Root against Carbon Tetrachloride-Induced Liver Damage in Mice

Figure 2

Protective effects of the TSAV pretreatment on CCl₄-induced liver damage. Histological examination was performed under a light microscope (original magnification: ×100) with HE staining on liver tissues. Group I: control; Group II: CCl₄; Group III: TSAV 50 mg/kg + CCl₄; Group IV: TSAV 100 mg/kg + CCl₄; Group V: TSAV 200 mg/kg + CCl₄; Group VI: silymarin 200 mg/kg + CCl₄. Blue, green, and black arrows indicate cell necrosis, inflammatory infiltration, and nuclear pyknosis, respectively.

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