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Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 236539, 12 pages
http://dx.doi.org/10.1155/2012/236539
Research Article

Sarcandra glabra Extract Reduces the Susceptibility and Severity of Influenza in Restraint-Stressed Mice

1Department of Medicine, Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, China
2Institute of Biomedical and Health Engineering, Translational Medicine Research and Development Center, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China
3State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
4Pharmacology Laboratory of Traditional Chinese Medicine, Guangdong Provincial Institute of Traditional Chinese Medicine, Guangzhou 510095, China

Received 5 July 2012; Revised 12 September 2012; Accepted 20 September 2012

Academic Editor: Seong-Gyu Ko

Copyright © 2012 Hui-Juan Cao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The Sarcandra glabra extract (SGE) was performing well in clinical practice and showed potentials in the therapy of influenza. However, relative experiment data for this effective clinical consequence was limited through general animal model. In this study, we also evaluated the effects of SGE against H1N1 influenza in infected normal mice. Although, SGE treatment could improve health status when compared to virus control group. However, our study results showed that SGE couldn’t reduce morbidity, mortality and prolong survival time. Thus, these data suggested that the effects of SGE against influenza were difficult to evaluate through general mouse model.

  1. Supplementary Material