JCM-16021, a Chinese Herbal Formula, Attenuated Visceral Hyperalgesia in TNBS-Induced Postinflammatory Irritable Bowel Syndrome through Reducing Colonic EC Cell Hyperplasia and Serotonin Availability in Rats

<table>Effect of JCM-16021 on colonic TPH expression in PI-IBS rats. Western immunoblots of TPH and the statistical analysis of protein level showed that JCM-16021 significantly decreased the colonic TPH expression in PI-IBS rats. Data are shown as mean ± S.E.M., <svg height="11.075" id="M19" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.075" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> per group. <svg height="19.65" id="M20" style="vertical-align:-3.276pt" version="1.1" viewbox="0 0 70.224998 19.65" width="70.224998" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus PI-IBS rats (<i>t</i>-test).</table>

Evidence-Based Complementary and Alternative Medicine

fig3

Figure 3

Figure 3: JCM-16021, a Chinese Herbal Formula, Attenuated Visceral Hyperalgesia in TNBS-Induced Postinflammatory Irritable Bowel Syndrome through Reducing Colonic EC Cell Hyperplasia and Serotonin Availability in Rats 

Figure 3 | JCM-16021, a Chinese Herbal Formula, Attenuated Visceral Hyperalgesia in TNBS-Induced Postinflammatory Irritable Bowel Syndrome through Reducing Colonic EC Cell Hyperplasia and Serotonin Availability in Rats 