Table 1: Mineral density and bone histomorphometric parmeters of proximal tibial cancellous bone.

Groups Sham OVXNYLICAEBHEXD

BMD (g/cm2)0.26 ± 0.01* 0.25 ± 0.01 0.26 ± 0.01*0.26 ± 0.01*0.26 ± 0.01* 0.26 ± 0.01*
Trabecular area ratio (%)21.37 ± 3.42**5.32 ± 1.09 19.04 ± 3.28**10.69 ± 2.22**13.82 ± 3.71**18.33 ± 2.47**
Trabecular thickness (μm )62.42 ± 6.06*43.57 ± 3.40 63.75 ± 6.39*56.54 ± 4.72*54.71 ± 5.16*60.78 ± 7.02*
Trabecular number (#/mm)3.17 ± 0.47**1.31 ± 0.22 2.79 ± 0.31**1.84 ± 0.24 2.34 ± 0.41**2.67 ± 0.28**
Trabecular separation (μm )209.73 ± 40.40**1007.36 ± 127.63 342.57 ± 37.33**631.77 ± 58.61*573.75 ± 62.31*441.81 ± 51.26*
MAR (μm/d)0.59 ± 0.19**1.18 ± 0.24 0.77 ± 0.11*1.26 ± 0.19 1.08 ± 0.22 0.81 ± 0.19*
BFR/BS (mcm/d*100)14.62 ± 1.85** 36.88 ± 4.71 17.62 ± 2.02**31.65 ± 8.76 33.82 ± 4.71 18.23 ± 2.57*
BFR/BV (%/year)139.62 ± 24.86**302.55 ± 46.37 163.18 ± 25.72**314.82 ± 28.66 317.65 ± 47.51 208.39 ± 26.12*
Osteoclast number (#/mm)7.47 ± 1.25**18.84 ± 3.67 8.84 ± 2.24**9.96 ± 2.42**9.21 ± 1.68**7.96 ± 2.19**

The data represent the mean ± standard deviation ( ), *P < 0.05, **P < 0.01 compared with OVX group.