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Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 254571, 9 pages
http://dx.doi.org/10.1155/2012/254571
Research Article

Treatment of Common Cold Patients with the Shi-Cha Capsule: A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Dose-Escalation Trial

1Pneumology Group, Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, West China School of Medicine, Sichuan University, 37 Guoxue Lane, Sichuan Province, Chengdu 610041, China
2Division of Clinical Pharmacology, West China Hospital, West China School of Medicine, Sichuan University, 37 Guoxue Lane, Sichuan Province, Chengdu 610041, China
3Department of Radiation Oncology, Tianjin Medical University Cancer Institute & Hospital, Tianjin 300060, China
4Department of Respiratory Medicine, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China
5Department of Respiratory Medicine, Affiliated Hospital of Jiangxi College of Traditional Chinese Medicine, Nanchang 330006, China
6Department of Respiratory Medicine, Shanghai Traditional Chinese Medicine Hospital, Shanghai 200071, China
7Department of Respiratory Medicine, The First Affiliation Hospital of Guangzhou Medical University, Guangzhou 510405, China

Received 23 September 2012; Accepted 15 November 2012

Academic Editor: Minawaer Abudu

Copyright © 2012 Jing Chang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Material 1: The flow chart of study procedures. Summary, all patients were examined by one of the clinical study respiratory experts and were enrolled into the study according to the inclusion and exclusion criteria described. In light of the study procedure, patients were seen by a respiratory expert at baseline, day 4, and day 10. During each visit, patients were interviewed by the respiratory expert to ascertain symptoms, compliance, and occurrence of adverse events. In addition, they were in contract with the enrolling research assistant and respiratory expert by telephone throughout the study except for interview.

Supplementary Material 2: The symptom questionnaire. Summary, Patients completed the symptom questionnaire from baseline to day 10 after treatment. These data provided an assessment of all symptom duration, main symptom duration, minor symptom duration, main symptom score, minor symptom score, and cumulative symptom score. The questionnaire consisted of eight symptoms: avertion to cold, clear nasal discharge, arthralgia of extremities, fever, headache, stuffy nose, sneezing, and spiritlessness and weakness. The first two symptoms were main symptom for which the patients provided a graded score (not at all = 0, mild = 3, moderate = 6, severe = 9). The last six symptoms were minor symptom for which the patients provided a graded score (not at all = 0, mild = 1, moderate = 2, severe = 3). The cumulative symptom score was the main symptom score plus the minor symptom score. In addition, tongue proper, tongue fur, and pulse were also assessed

  1. Supplementary Material