256561.fig.007
Figure 7: Q-RT-PCR validation of novel therapeutic markers. Five candidate markers, Btg2, Egr1, Oldr1, Nrg1, and Hmgcs1, were validated by Q-RT-PCR and are illustrated on 3D mesh plots. 18s rRNA from each sample was quantified at the same time as the target gene. Btg2, Egr1, Oldr1, Nrg1 were upregulated with liver damage and recovered following both drug treatments. However, Hmgcs1 was downregulated and recovered after GP administration only. The five different groups are shown as normal (C), DMN treatment (D), GP treatment only (M), Silymarin therapeutic (S), and GP-therapeutic (Z).