Hypoglycemic and Hypolipidemic Effects of Ethanolic Extract of Mirabilis jalapa L. Root on Normal and Diabetic Mice

Table 4

Effects of repeated EEM administration on glycogen and TG contents in liver and skeletal muscle of normal and diabetic mice.

Group	Liver		Skeletal muscle
	Glycogen (mg/g)	TG (μmol/g)	Glycogen (mg/g)	TG (μmol/g)
Normal control	12.43±1.19	3.39±0.28	1.66±0.16	0.126±0.009
Normal + 2 g/kg EEM	12.36±1.05	3.45±0.16	1.55±0.14	0.123±0.007
Normal + 4 g/kg EEM	12.67±1.00	3.50±0.25	1.72±0.17	0.131±0.011
Normal + 8 g/kg EEM	12.75±1.33	3.35±0.27	1.70±0.15	0.131±0.008
Normal + glibenclamide	12.81±1.06	3.28±0.26	1.71±0.12	0.128±0.007
Diabetic control	6.86±0.41 *	5.28±0.21 *	2.75±0.20 *	0.226±0.016 *
Diabetic + 2 g/kg EEM	7.28±0.36	5.29±0.34	2.75±0.28	0.215±0.019
Diabetic + 4 g/kg EEM	9.38±1.14^#	4.24±0.37^#	2.04±0.22^#	0.170±0.008^#
Diabetic + 8 g/kg EEM	9.79±0.99^#	4.09±0.30^#	2.03±0.17^#	0.164±0.011^#
Diabetic + glibenclamide	10.81±0.77^#	5.15±0.33	1.79±0.13^#	0.221±0.020

Data are expressed as mean ± SD, 𝑛=10 mice per group. *𝑃<0.01 when compared to normal control. ^#𝑃<0.01 when compared to diabetic control.