Mulberry Fruit Extract Protects against Memory Impairment and Hippocampal Damage in Animal Model of Vascular Dementia

Table 2

Effect of mulberry fruit extract on oxidative stress markers.

Group	SOD	Catalase	GSH-Px	MDA
	(μ/mg·protein)	(μ/mg·protein)	(μ/mg·protein)	(μ/mg·protein)
Vehicle + MCAO	1.65±0.18	12.84±1.54	0.52±0.10	2.45±0.80
Donepezil 1 mg + MCAO	1.82±0.33	36.46±7.11^∗∗∗	0.95±0.28	1.68±0.39
Mulberry 2 mg + MCAO	2.65±0.41	15.22±4.05	0.78±0.22	1.55±0.32
Mulberry 10 mg + MCAO	2.47±0.55	19.80±6.65	1.19±0.36^∗	0.98±0.28^∗
Mulberry 50 mg + MCAO	2.77±0.51^∗	13.88±3.64	1.33±0.16^∗	1.51±0.25

Data are the mean ± SEM. *𝑃<.05, **𝑃<.01, ***𝑃<.001 compared with vehicle treated group.
Abbreviations: SOD: Superoxide dismutase; GSH-Px: Glutathione peroxidase; MDA: Malondialdehyde.