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Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 271606, 15 pages
http://dx.doi.org/10.1155/2012/271606
Research Article

Beneficial Effect of Shikonin on Experimental Colitis Induced by Dextran Sulfate Sodium in Balb/C Mice

1Departamento de Farmacologia, Facultat de Farmàcia, Universitat de València, Burjassot, 46100 Valencia, Spain
2Departamento de Patologia, Facultat de Medicina, Universitat de València, 46100 Valencia, Spain

Received 2 October 2012; Accepted 3 December 2012

Academic Editor: Cassandra L. Quave

Copyright © 2012 Isabel Andújar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [7 citations]

The following is the list of published articles that have cited the current article.

  • Marta Marin, Rosa Maria Giner, and Jose-Luis Rios, “Intestinal anti-inflammatory activity of ellagic acid in the acute and chro nic dextrane sulfate sodium models of mice colitis,” Journal of Ethnopharmacology, vol. 150, no. 3, pp. 925–934, 2013. View at Publisher · View at Google Scholar
  • Isabel Andujar, Jose Luis Rios, and Rosa Maria Giner, “Pharmacological Properties of Shikonin - A Review of Literature since 2002,” Planta Medica, vol. 79, no. 18, pp. 1685–1697, 2013. View at Publisher · View at Google Scholar
  • Marta Marin, Rosa Maria Giner, and Jose-Luis Rios, “Protective Effect of Apocynin in a Mouse Model of Chemically-Induced Coliti s,” Planta Medica, vol. 79, no. 15, pp. 1392–1400, 2013. View at Publisher · View at Google Scholar
  • I. Andujar, J. L. Rios, and R. M. Giner, “Shikonin promotes intestinal wound healing in vitro via induction of TGF-be ta release in IEC-18 cells,” European Journal Of Pharmaceutical Sciences, vol. 49, no. 4, pp. 637–641, 2013. View at Publisher · View at Google Scholar
  • Ting Li, Fenggen Yan, Rui Wang, Hua Zhou, and Liang Liu, “Shikonin Suppresses Human T Lymphocyte Activation through Inhibition of IKKβ Activity and JNK Phosphorylation,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, pp. 1–13, 2013. View at Publisher · View at Google Scholar
  • Xiao-Li Wu, Chu-Wen Li, Hai-Ming Chen, Zu-Qing Su, Xiao-Ning Zhao, Jian-Nan Chen, Xiao-Ping Lai, Xiao-Jun Zhang, and Zi-Ren Su, “Anti-Inflammatory Effect of Supercritical-Carbon Dioxide Fluid Extract from Flowers and Buds of Chrysanthemum indicum Linnén,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, pp. 1–13, 2013. View at Publisher · View at Google Scholar
  • Yuanyuan Xu, Xuegang Xu, Xinghua Gao, Hongduo Chen, and Long Geng, “Shikonin suppresses IL-17-induced VEGF expression via blockage of JAK2/STAT3 pathway,” International Immunopharmacology, 2014. View at Publisher · View at Google Scholar